The care of Corydoras gracilis is largely similar to the requirements for keeping other species of Cory catfish. Key aspects include maintaining clean and warm water, preventing the accumulation of organic waste, and providing a complete diet. Although the choice of decorations is usually not critical, in this case, it is recommended to recreate an environment resembling their natural habitat. It is desirable to have shelters, which can be branches, snags, and roots, as well as a leaf substrate at the bottom. The use of leaves from certain trees has a beneficial effect on the chemical composition of the water, helping to lower pH and increase the concentration of tannins. As for nutrition, a varied diet is crucial for maintaining the health of the fish. Their daily menu can consist of dry foods, supplemented with frozen or live foods such as brine shrimp, bloodworms, or daphnia. In terms of behavior and compatibility, these catfish feel more comfortable in a group consisting of 4–6 individuals. They get along well with peaceful and calm fish of similar size. However, it is worth avoiding proximity to territorial, and even more so, aggressive species.