For a group of 4–5 fish, the optimal aquarium size should start from 300 liters. The aquarium setup can be anything, but it is important to provide hiding places, for example, from driftwood. Dim lighting is recommended. Since Mylossoma is a "vegetarian," it tends to damage the soft parts of live plants and can completely destroy plant cover. It is advisable to use artificial green plants or try planting plants with tough leaves, such as Anubias. For long-term keeping, it is critically important to maintain high water quality, avoiding the accumulation of organic waste such as food residues and excrement. To do this, regularly change part of the water for fresh, combining this with siphoning the substrate, and ensure the continuous operation of the filtration system. Mylossoma duriventre can adapt to a fairly wide range of pH and dH values, which simplifies water preparation for the aquarist. The diet changes with age: fry and young fish feed mainly on aquatic invertebrates (crustaceans, insect larvae, worms, and others), while adults switch to plant-based food, the basis of which is plant leaves, fallen fruits, and seeds. Accordingly, the choice of aquarium feeds should take into account the age of the fish. Young fish in the aquarium can consume universal feeds. If there are no stripes on the fish's body, it is an adult individual that needs to be offered plant-based feeds (with algae, vegetables). Many manufacturers offer special feeds for such fish in the form of flakes and granules. To diversify the diet, ordinary feeds with protein supplements, as well as live or frozen bloodworms and Artemia, can be added.