When choosing Megalancistrus parananus, it is important to consider the impressive size of the adult, reaching almost 60 cm, so make sure the aquarium in the store meets the fish's needs. Inspect the skin: there should be no white spots, ulcers, bruises, or damage to the spiny fin rays on the body. A healthy fish is active during twilight hours, has clear eyes, and fins pressed tightly against its body. Avoid individuals with sunken bellies, which may indicate emaciation or internal parasitic infections, and also ensure that the fish does not show signs of apathy or labored breathing.