For a group of 10 fish, the optimal aquarium volume is 50–60 L. It is desirable to keep Nannostomus harrisoni in conditions that are as close as possible to their natural habitat. The fish will look most expressive among snags and thickets of aquatic vegetation, including floating species, where they often gather. Lighting should be subdued, so shade-loving plants are chosen for decoration. An important, though not mandatory, decorative element is the leaves of some trees, which are placed on the bottom. As they decompose, conditions similar to natural bodies of water are created: the water is enriched with tannins and acquires a characteristic brownish tint. In addition, leaves serve as an ideal basis for the formation of colonies of beneficial microorganisms, such as paramecia, which are a valuable additional food source for fry. Long-term and successful keeping of the fish is ensured by maintaining stable water parameters within acceptable hydrochemical limits. For this, the aquarium is equipped with all necessary equipment, part of the water is replaced with fresh water weekly, organic waste is regularly removed, and other mandatory procedures are performed.