Breeding Nannostomus marilynae is possible in a home aquarium, although it involves certain difficulties. The main problems include the tendency of adult fish to eat their own fry, as well as difficulties in feeding very small fry. In an artificial environment, there is no pronounced breeding season. In a large group consisting of dozens of individuals, fry can appear quite frequently, as females spawn at different times. During spawning, females scatter their eggs among plant thickets, after which they show no parental care. As mentioned, given the opportunity, the fish may eat the eggs or newly hatched fry. To preserve the offspring, it is recommended to transfer them or the unhatched eggs to a separate aquarium with similar water parameters. Fry should be fed specialized powdered foods, suspensions, and, if possible, infusoria.