For keeping one or two fish, the minimum aquarium volume should be 50–60 L. Fish raised in captivity are usually not demanding regarding decor and can comfortably exist even in a fairly empty tank, as is often seen in pet stores before sale. However, in the long term, such keeping can lead to their coloration fading. The Two-striped Apistogramma will look much more harmonious in a setup that mimics its natural habitat. It is recommended to use a sandy substrate, place many snags and aquatic plants, forming secluded corners for hiding. Lighting should be subdued. When planning breeding, it is important to provide reliable hiding places, such as caves or grottoes, where females can hide with their fry. Experienced aquarists often add leaves from certain trees to the aquarium not only to give the decor a more natural look but also to create the necessary chemical composition of the water. The latter is achieved by the release of tannins from decomposing leaves, mimicking natural processes. Successful keeping largely depends on maintaining stable water parameters within the permissible range of temperatures and hydrochemical indicators characteristic of this species. For this, the aquarium must be equipped with appropriate technical equipment (filters, heaters, aerators, etc.) and regular maintenance procedures must be carried out. These include weekly partial water changes (10–15% of the total volume) with fresh water, monitoring nitrite, nitrate, and ammonia levels, removing organic waste, and prophylactic inspection of equipment.